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Experiments

Compound Investigated event Experiment type Concentration Cell line Organism Animal model Stat protein Details
SH4-54 Influence on protein binding to DNA EMSA 1.00 µM U251MG Homo sapiens STAT3:STAT3
SH4-54 Influence on protein binding to DNA EMSA 1.00 µM U373MG Homo sapiens STAT3:STAT3
SH4-54 Influence on protein binding to DNA EMSA 1.00 µM MDA-MB-231 Homo sapiens STAT3:STAT3
SH4-54 Influence on protein binding to DNA EMSA 1.00 µM DU145 Homo sapiens STAT3:STAT3
SH4-54 Influence on protein binding to DNA EMSA 3.00 µM U251MG Homo sapiens STAT3:STAT3
SH4-54 Influence on protein binding to DNA EMSA 3.00 µM U373MG Homo sapiens STAT3:STAT3
SH4-54 Influence on protein binding to DNA EMSA 3.00 µM MDA-MB-231 Homo sapiens STAT3:STAT3
SH4-54 Influence on protein binding to DNA EMSA 3.00 µM DU145 Homo sapiens STAT3:STAT3
SH4-54 Influence on protein binding to DNA EMSA 10.00 µM U251MG Homo sapiens STAT3:STAT3
SH4-54 Influence on protein binding to DNA EMSA 10.00 µM U373MG Homo sapiens STAT3:STAT3
SH4-54 Influence on protein binding to DNA EMSA 10.00 µM MDA-MB-231 Homo sapiens STAT3:STAT3
SH4-54 Influence on protein binding to DNA EMSA 10.00 µM DU145 Homo sapiens STAT3:STAT3
SH4-54 Influence on protein binding to DNA EMSA 1.00 µM U87MG Homo sapiens STAT3:STAT3
SH4-54 Influence on protein binding to DNA EMSA 3.00 µM U87MG Homo sapiens STAT3:STAT3
SH4-54 Influence on protein binding to DNA EMSA 10.00 µM U87MG Homo sapiens STAT3:STAT3
SH4-54 Influence on protein binding to DNA EMSA 1.00 µM SF295 Homo sapiens STAT3:STAT3
SH4-54 Influence on protein binding to DNA EMSA 3.00 µM SF295 Homo sapiens STAT3:STAT3
SH4-54 Influence on protein binding to DNA EMSA 10.00 µM SF295 Homo sapiens STAT3:STAT3
SH4-54 Influence on protein binding to DNA EMSA 5.00 µM U251MG Homo sapiens STAT3:STAT3
SH4-54 Influence on protein binding to DNA EMSA 5.00 µM MDA-MB-231 Homo sapiens STAT3:STAT3
SH4-54 Influence on protein activty Western Blot 1.00 µM U251MG Homo sapiens p-STAT3(Y705)
SH4-54 Influence on protein activty Western Blot 3.00 µM U251MG Homo sapiens p-STAT3(Y705)
SH4-54 Influence on protein activty Western Blot 10.00 µM U251MG Homo sapiens p-STAT3(Y705)
SH4-54 Influence on protein activty Western Blot 1.00 µM U373MG Homo sapiens p-STAT3(Y705)
SH4-54 Influence on protein activty Western Blot 3.00 µM U373MG Homo sapiens p-STAT3(Y705)
SH4-54 Influence on protein activty Western Blot 10.00 µM U373MG Homo sapiens p-STAT3(Y705)
SH4-54 Influence on protein activty Western Blot 1.00 µM MDA-MB-231 Homo sapiens p-STAT3(Y705)
SH4-54 Influence on protein activty Western Blot 3.00 µM MDA-MB-231 Homo sapiens p-STAT3(Y705)
SH4-54 Influence on protein activty Western Blot 10.00 µM MDA-MB-231 Homo sapiens p-STAT3(Y705)
SH4-54 Influence on protein activty Western Blot 1.00 µM U251MG Homo sapiens STAT3
SH4-54 Influence on protein activty Western Blot 3.00 µM U251MG Homo sapiens STAT3
SH4-54 Influence on protein activty Western Blot 10.00 µM U251MG Homo sapiens STAT3
SH4-54 Influence on protein activty Western Blot 1.00 µM U373MG Homo sapiens STAT3
SH4-54 Influence on protein activty Western Blot 3.00 µM U373MG Homo sapiens STAT3
SH4-54 Influence on protein activty Western Blot 10.00 µM U373MG Homo sapiens STAT3
SH4-54 Influence on protein activty Western Blot 1.00 µM MDA-MB-231 Homo sapiens STAT3
SH4-54 Influence on protein activty Western Blot 3.00 µM MDA-MB-231 Homo sapiens STAT3
SH4-54 Influence on protein activty Western Blot 10.00 µM MDA-MB-231 Homo sapiens STAT3
SH4-54 Influence on protein activty Western Blot 5.00 µM U251MG Homo sapiens p-STAT3(Y705)
SH4-54 Influence on protein activty Western Blot 5.00 µM U373MG Homo sapiens p-STAT3(Y705)
SH4-54 Influence on protein activty Western Blot 5.00 µM MDA-MB-231 Homo sapiens p-STAT3(Y705)
SH4-54 Influence on protein activty Western Blot 5.00 µM U251MG Homo sapiens STAT3
SH4-54 Influence on protein activty Western Blot 5.00 µM U373MG Homo sapiens STAT3
SH4-54 Influence on protein activty Western Blot 5.00 µM MDA-MB-231 Homo sapiens STAT3
SH4-54 Influence on proetin acivity in presnce of IL-6 Western Blot 10.00 µM MDA-MB-231 Homo sapiens p-STAT3(Y705)
SH4-54 Influence on proetin acivity in presnce of IL-6 Western Blot 10.00 µM MDA-MB-231 Homo sapiens STAT3
SH4-54 Influence on protein binding to DNA EMSA 8.00 µM U251MG Homo sapiens STAT3:STAT3 (nuclear)
SH4-54 Influence on cell viability CyQUANT cell proliferation assay 2.00 µM MDA-MB-231 Homo sapiens
SH4-54 Influence on cell viability CyQUANT cell proliferation assay 4.00 µM MDA-MB-231 Homo sapiens
SH4-54 Influence on cell viability CyQUANT cell proliferation assay 6.00 µM MDA-MB-231 Homo sapiens